Marc
Lipsitch is a professor of epidemiology and director of the Center for
Communicable Disease Dynamics at the Harvard T.H. Chan School of Public
Health. Tom Inglesby is director of the Center for Health Security and
an environmental health and engineering professor at Johns Hopkins
Bloomberg School of Public Health.
In
2014, U.S. officials imposed a moratorium on experiments to enhance
some of the world’s most lethal viruses by making them transmissible by
air, responding to widespread concerns that a lab accident could spark a
global pandemic. Most infectious-disease studies pose modest safety
risks, but given that these proposed experiments intended to create a
highly contagious flu virus that could spread among humans, the
government concluded the work should not go on until it could be
approved through a specially created, rigorous review process that
considered the dangers.
Apparently, the government has decided the research should now move ahead. In the past year, the U.S. government quietly greenlighted
funding for two groups of researchers, one in the United States and the
other in the Netherlands, to conduct transmission-enhancing experiments
on the bird flu virus as they were originally proposed before the
moratorium. Amazingly, despite the potential public-health consequences
of such work, neither the approval nor the deliberations or judgments
that supported it were announced publicly. The government confirmed them
only when a reporter learned about them through non-official channels.
This
lack of transparency is unacceptable. Making decisions to approve
potentially dangerous research in secret betrays the government’s
responsibility to inform and involve the public when approving
endeavors, whether scientific or otherwise, that could put health and :
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